Sensing Business

Contributes to the development of infertility treatment by application of electrochemical measurement technology.

Non-Invasive
Easy Operation
Objective Assessment
The Cell respiration assay system -3.0 (Cras-3.0) is a measurement system applied with the latest electrochemical measurement technology.
By measuring respiration of embryo, quantitative evaluation of embryo is possible.

Non-Invasive

Scaning up and down with a microprobe(a tip diameter of approximately φ5μm) the side of embryo placed in inverted conical well filled with measurement solution thereby the gradient of dissolved oxygen concentration from near to far the embryo is measured electrochemically, and the respiration rate is calculated by the theoretical formula.
There is no effect on embryo viability or development because it can measure non-invasively without touching the embryo directly.
A general HTF medium can be used as the measurement solution.

Easy Operation

Operation of CRAS-3.0 is done using specialized software. Its high-performance camera allows the user to easily perform high-precision operation in units of 1μm minimum by the click of a mouse while checking the position of the embryo and the microprobe in real time. Since all movement distances can be confirmed by numerical values, accurate and highly reproducible measurement is made possible.

The specially designed plate used for the measurement has 6 wells to set the embryo, and the respiration rate of up to 5 (*1) embryos can be measured continuously.

Objective Assessment

CRAS can quantitatively evaluate embryo respiration. An objective index is added to the conventional method of morphological observation of the embryo, which contributes to improvement of evaluation accuracy.